Home - Health - High Monocyte Count – Symptoms, Diagnosis, And Management

High Monocyte Count – Symptoms, Diagnosis, and Management

Monocytes are a type of white blood cells that are responsible for isolating and cleaning up germs and other harmful microbes from the tissues in the body. They also clean up dead cells and assist in the immune response. Typically, monocytes make up a very small percentage of the total white blood cells in the body. They are present in a concentration of 2-8% (or 100 to 700 per mm3).

High Monocyte Count – Symptoms, Diagnosis, and Management

What is monocytosis?
When the body’s monocyte count goes above normal levels, it is called monocytosis. This condition is often closely associated with infectious and autoimmune diseases, blood disorders, and certain types of cancer.

Some conditions that can cause monocytosis include endocarditis, tuberculosis, malaria, syphilis, collagen vascular disorders, sarcoidosis, protozoal or rickettsial infections, bone marrow recovery, chronic stress, heart attack, splenectomy, myeloproliferative diseases, or viral infections.

Symptoms of monocytosis
People with a high monocyte count may not experience any symptoms. Generally, symptoms are related to the underlying cause and may include:

  • Fatigue
  • Weakness
  • Swelling
  • Fever

To confirm a high monocyte count, doctors prescribe a blood differential test. This test determines the level of each type of white blood cell in the body and informs of any abnormalities in these cells. Normal ranges of the other types of white blood cells in the body are as follows:

  • Basophils secrete chemicals such as histamine to help the body’s immune response. They make up 0.5 to 1 percent (25 to 100 per mm3) of one’s white blood cells.
  • Eosinophils aid the body’s allergic response and are particularly important for killing cancer and parasitic cells. They make up 1 to 4 percent (50 to 500 per mm3) of white blood cells in the body.
  • Lymphocytes comprise about 20 to 40 (1000 to 4000 per mm3) percent of white blood cells and are responsible for creating antibodies that fight against bacteria and viruses.
  • Neutrophils are the most common type of white blood cells, making up 55 to 70 percent (2500 to 8000 per mm3) of their content in the body. They form the first line of defense against bacteria and fungi.
  • Young neutrophils (band cells)  are immature, commonly produced white blood cells. They make up between 0 and 3 percent of the white blood cell content in the body and are responsible for fighting infections and promoting healing.

A monocyte count of over 10% (or 800 mm3) is considered high and may be an indication of an immune system response to another condition.

Diagnosis and treatment
Based on one’s symptoms and physical examination, doctors may suggest getting additional diagnostic tests such as a chest X-ray, blood smear, urine culture, blood culture, throat culture, and/or a bone marrow biopsy. Depending on the results from these tests, the doctor will draw a diagnosis, such as an infection or health condition that requires attention. The most common tests prescribed are:

  • Complete blood count (CBC)
    In this test, a sample of one’s blood is taken to analyze the total number of white blood cells present.
  • Peripheral blood smear
    In this test, a blood sample is analyzed under a microscope to assess the cell size and shape. It helps narrow down the list of potential underlying causes that may result in a high monocyte count.
  • Absolute monocyte count
    This test measures the number of monocytes in the blood sample. It is based on multiplying the number of monocytes in the CBC by the total number of white blood cells in the sample to examine whether the monocyte count is low, normal, or high.

The treatment for monocytosis will depend on the underlying causes. Some common treatment options include:

  • Symptom management for viral infections
  • Using antibiotics to treat bacterial infections
  • Chemotherapy, radiation therapy, stem cell transplant, supportive therapy, or surgery for treating blood cancer
  • Test-based prescriptions for other parasitic conditions

For some conditions, especially some forms of leukemia, blood levels may need to be monitored regularly to monitor the effect of the treatment.

Steps to maintain a healthy monocyte count
Besides formal treatment, one may also use the following techniques to keep monocytes in a healthy range:

  • Regular exercise
    Some studies suggest that regular exercise can help maintain monocyte counts at optimal levels and bolster overall health with age.
  • Eating anti-inflammatory foods
    Monocytes respond to inflammation in the body. To lower their levels, eating anti-inflammatory foods can help. Some options include olive oil, green leafy vegetables such as kale, spinach, and collard greens, tomatoes, strawberries, blueberries, cherries, oranges, nuts such as almonds and walnuts, and fatty fish such as salmon, tuna, sardines, and mackerel.
    At the same time, avoiding inflammatory foods such as processed or red meats, refined carbohydrates, fried foods, soda, and other sugar-filled beverages, margarine, shortening, and lard is advisable.
  • Reduce stress levels
    It is also important to regulate stress levels and get adequate rest to regulate the monocyte count in the body.

A high monocyte count may indicate a serious health condition, infection, or stress. It is advisable to consult a doctor to diagnose the underlying cause and discuss treatment options.

Disclaimer:
The content of the articles discussing symptoms, treatments, health conditions, and side effects is solely intended for informational purposes. It is imperative that readers do not interpret the information provided on the website as professional advice. Readers are requested to use their discretion and refrain from treating the suggestions or opinions provided by the writers and editors as medical advice. It is important to seek the help of licensed and expert healthcare professionals when necessary.
Previous Article
Next Article

Featured Articles

An Overview Of Colon Polyps

An Overview Of Colon Polyps

An overview of colon polyps Colon polyps are small clumps of cells formed on the lining of the colon. The majority of these polyps tend to be harmless, but with time, there are certain polyps that can easily grow into colon cancer. This is a serious condition, especially when found in the later stages. Almost any individual can develop colon polyps. People who are over 50 years of age are at an increased risk of suffering from this condition. Even smokers and overweight individuals or people with a family or personal history of colon polyps might be at an increased risk of suffering from this condition. Colon polyps – causes are slightly known, but this condition rarely causes any symptoms. Therefore, for individuals who are at risk of developing the condition, it is important to have screening tests on a regular basis. These will include a colonoscopy. Polyps found in the early stages can conveniently be removed. They can be removed completely in a very safe manner. Regular screening is the best step for the prevention of colon polyps. What are the colon polyps – causes? Doctors do not exactly know the causes of colon polyps, but they are of the view that polyps are a result of abnormal tissue growth. The human body develops healthy cells in a periodic manner, thus replacing the old cells that tend to be damaged or are no longer required. The division and growth of these new cells is regulated. However, there are cases when the new cells develop and then divide before they are actually needed. It is this excessive growth that results in polyps. Packaged red meat is also one of the most common colon polyps – causes. Fiber deficiency in the body. High-fat diet taken in excessive amounts. Smoking cigarettes. Obesity is also one of the major colon polyps – causes. Inherited conditions such as Gardener syndrome, familial adenomatous polyposis, and Peutz-Jeghers syndrome might also put an individual at an increased risk of having colon polyps. What signs and symptoms do colon polyps show? Majority of the individuals suffering from colon polyps do not show any symptoms. They are actually unaware of the fact that they have polyps, because they feel very well. Bleeding from the rectum is one of the most common symptoms of colon polyps. Blood in the stool can also be a sign of colon polyps. Blood might make stool look black, or there can be red streaks in stool. A feeling of tiredness due to anemia and not having sufficient iron in the body are common symptoms. It is the bleeding from the polyps that can result in an iron deficiency and anemia. Several other health issues might also result in these signs. Nevertheless, if rectum bleeding or blood in the stool are everyday phenomena, a consultation with a doctor is vital. How can colon polyps be prevented? Knowing the colon polyps – causes can help prevent the condition. However, there are other important steps that can be followed in trying to prevent this condition. They are as listed: Regular screenings. Lifestyle changes can also be of help in doing away with the colon polyps – causes, and, consequently, prevent them. Adopting healthy habits such as eating fruits, whole grains, and vegetables and reducing fat intake can help in the prevention of colon polyps. Limiting the intake of alcohol and quitting tobacco. Staying active physically and maintaining a healthy body weight is also important. When should one see a doctor? A general physician must be consulted in case of the following: Blood in the stool Abdominal pain Changes in bowel habits for more than a week It is important for one to have a word with their physician regarding their intake of vitamin D and calcium. This is because studies have proved that increasing the intake of food items rich in vitamin D and calcium can help prevent the recurrence of polyps. However, this is not completely clear. It is important to consider all the options, especially if one is at a very high risk of suffering from colon polyps.
Read More
The Types Of Colon Polyps And Their Prevention

The Types Of Colon Polyps And Their Prevention

The types of colon polyps and their prevention Growths that occur on the inner lining of the colon (large intestine) and usually protrude into the colon are known as colon polyps. They form when the genetic material within the cells that line the colon changes and becomes abnormal. Under normal circumstances, the immature cells that line the colon multiply, mature, and then die in a timely fashion. On the other hand, the genetic changes in the lining cells prevent the cells from maturing, and they don’t die. Resultantly, immature and genetically abnormal cells start accumulating in the colon, eventually resulting in the formation of polyps. This article intends to raise awareness about colon polyps, its types, symptoms, diagnosis, the colon polyps – causes, and more. What are the types of colon polyps? Inflammatory colon polyps : Also known as false polyps, it is mostly found in people who have inflammatory bowel diseases (IBD), such as Crohn’s disease or ulcerative colitis. These polyps are inflammatory manifestations of IBD, are benign, and are unlikely to become cancerous. Adenomatous colon polyps : Also known as adenomas, this type of colon polyps make up about 70% of all polyps found in the colon. They can become cancerous, but the process takes years. Hyperplastic colon polyps : The term hyperplasia means fast growth, which indicates an abnormal increase in the number of cells resulting in the gross enlargement of the colon polyp. Despite the rapid growth, hyperplastic polyps have a low risk of turning cancerous. Villous adenoma : This type of colon polyp has a greater potential of becoming cancerous. It is estimated that approximately 30 percent of villous adenomas develop into a malignancy. These polyps require surgery for the removal of their cauliflower-like protrusions. What are the causes of colon polyps? Experts are not sure about the colon polyps – causes. However, the causes are believed to be a mix of environmental and genetic factors that result in an abnormal tissue growth. What are the known risk factors of colon polyps? Age : The risk of developing colon polyps tends to increase with age. Family history : A close relative with colon cancer or polyps raises the risk. Sex : Men have a slightly higher chance of developing polyps. Race : Black men and women have a higher risk. Alcohol : Alcohol consumption is closely linked to colon cancer risk and is known as one of the colon polyps – causes. Red meat : If not had in moderation, red meat can serve as one of the colon polyps – causes. Having too much red meat increases the risk of colorectal cancer as well. Lack of dietary fiber : A good intake of fiber has many benefits, including colon benefits. It decreases the risk of colon cancer. Smoking : Smoking increases the risk of all types of cancers, and colon polyps or cancer is no exception. Obesity : Obese people are at higher risk of developing colon polyps and cancer. How are colonic polyps diagnosed? The following tests help diagnose colon polyps: Colonoscopy Sigmoidoscopy Barium enema CT colonography Stool test What are the symptoms of colon polyps? Change in stool color Rectal bleeding Iron deficiency Anemia Change in bowel habits Abdominal pain Blood in the stool Fatigue How common are colon polyps? They are very common. They increase in prevalence as people age. If one has colon polyps, they are more likely to develop polyps elsewhere in the colon later. Only a small proportion of polyps cause symptoms or signs, which usually are the result of bleeding from the polyp. How can colon polyps be prevented? Adopt healthy habits : Adopt healthy habits and increase the intake of fruits, vegetables, and whole grains. Limit fat intake, alcohol consumption, and quit tobacco. Stay physically active and maintain a healthy weight. Avoid all the estimated colon polyps – causes. Seek advice if at high risk : If there’s a family history of colon polyps or its other risk factors affect one, seeking prompt medical advice and counseling is important. With regular colonoscopies, one can prevent the colon polyps – causes from developing, and hence preventing the colon from developing.
Read More
Carcinoid Neuroendocrine Tumors – Prognosis And Life Expectancy

Carcinoid Neuroendocrine Tumors – Prognosis And Life Expectancy

Carcinoid neuroendocrine tumors – Prognosis and life expectancy The neuroendocrine system is a complex regulatory mechanism comprised of cells spread throughout several organ systems, including our lungs and digestive system. As they have characteristics of both nerves and endocrine cells, they are called neuroendocrine cells. The nerve cells transmit signals using electrical impulses, whereas endocrine cells make thyroid and insulin-secreting glands. This article intends to discuss the carcinoid neuroendocrine tumor that starts in these cells in detail. What is a carcinoid neuroendocrine tumor? A carcinoid neuroendocrine tumor starts in the cells of the hormone-producing organs in our body. A carcinoid tumor is a type of neuroendocrine tumor that most commonly arises in the gastrointestinal system, which includes intestines, stomach, and esophagus. Carcinoid tumors account for about 1% to 2% of lung cancers. As carcinoid tumors originate from tissue that produces hormones, the main side effect of the condition is the inappropriate release of various hormones in the bloodstream. Carcinoid neuroendocrine tumor can arise in a number of locations categorized into three areas: the foregut, midgut, and hindgut. Lungs and stomach form the foregut area. The midgut comprises of the small intestine, colon, and appendix. The hindgut includes the end of the large bowel, the rectum, and genitourinary tract organs (ovaries and testes). What factors raise a person’s risk of developing a carcinoid tumor? A family history of multiple endocrine neoplasia type 1 : This hereditary condition increases an individual’s risk of developing tumors in the pituitary gland, pancreas, and parathyroid gland. Age : Age seems to be a major factor that plays an integral role, as children rarely develop carcinoid tumors; the average diagnosis age is 55 to 65 years for this condition. Race and gender : Carcinoid tumors are more common among black people than white people, and black men have a higher risk than black women. White men and women have the same risk levels, and after treatment, women tend to live longer. Other medical conditions : Some medical conditions that damage the stomach and reduce acid production increase the risk of developing a carcinoid neuroendocrine tumor. What are the symptoms of a carcinoid tumor? Signs and symptoms of a carcinoid neuroendocrine tumor depend on where the tumor develops: Carcinoid tumors in the lungs : The symptoms of a tumor in the lungs are chest pain, wheezing, diarrhea, shortness of breath, skin flushing (redness and a feeling of warmth on the face and neck), weight gain, particularly around the midsection and back, and pink or purple marks on the skin, which look like stretch marks. Carcinoid tumors in the digestive tract : The symptoms, in this case, are abdominal pain, diarrhea, nausea and vomiting, intestinal blockage, causing an inability to pass stool, rectal bleeding and pain, and skin flushing. What are some effective management tips for the symptoms of carcinoid neuroendocrine tumors? Facial flushing : Avoid stress and ask your doctor about specific foods that cause facial flushing so that you can avoid them. Diarrhea : Ask your doctor for anti-diarrheal medication. Wheezing : Ask for medication that relaxes muscles in the lungs to make breathing easier. Heart problems : Discuss your heart issues with your doctor so that they can prescribe diuretics, which lower the blood pressure. Carcinoid syndrome : Use octreotide on prescription, which is the most effective medication to treat carcinoid syndrome. What is the prognosis for carcinoid neuroendocrine tumor? Carcinoid neuroendocrine tumors can be benign (non-cancerous) or malignant (cancerous). Benign carcinoid tumors are small and can be removed completely. They don’t come back and don’t spread to other parts of the body. They don’t produce any symptoms as well. Malignant carcinoid tumors are large, and their cells can invade and damage the surrounding tissues and organs. Additionally, malignant cells can enter the bloodstream or lymphatic system and can even form new tumors in other parts of the body. Lymph nodes, lungs, bone liver, and skin are the common sites for carcinoid metastases. Carcinoid tumors grow slowly in comparison to other cancers, such as lung, colon, pancreas, or liver cancer. Patients with larger malignant carcinoid tumors (with or without metastasis) can survive and have a good quality of life after proper treatment. Adenocarcinoids, a rare form of carcinoid tumors, are more aggressive than the typical malignant carcinoid tumors.
Read More
What Are The First Signs Of Liver Damage

What Are The First Signs Of Liver Damage

Liver damage – What are the first signs? On the right side of the abdomen, below your rib cage, is an organ called the liver. It is the size of a football and is one of the most important organs in the human body. The liver aids in the digestion of the food we eat and also helps in flushing out the toxins from our body. When there is any kind of disturbance in the normal liver functioning, then it can cause a significant damage to the human body. Once you start exhibiting the signs of liver damage, it is important to get the exact diagnosis and take the next steps accordingly. What are the causes of liver damage? There can be a number of causes for liver damage: Liver infection is one of the most common causes of liver damage. Viruses and parasites can cause infections that affect the normal functioning of the liver. Hepatitis is the most common liver infection, which includes Hepatitis A, Hepatitis B, and Hepatitis C. Some diseases will affect your immune system thereby damaging your liver too. This is called autoimmune hepatitis. Primary Sclerosing Cholangitis and Primary Biliary Cirrhosis are of the same kind. If you have inherited an abnormal gene from any of your parents or family members, it can lead to a build up of various substances in the body and hence can damage the liver. Build up of liver cancer can be a cause. A person who is an alcohol addict is more prone to liver damage. What are the first signs of liver damage? There can be several signs of a liver damage. Here are 10 signs of liver damage that you need to pay attention to: Your eyes and skin turning yellow, which is usually a sign of jaundice. Abdominal swelling and pain are also symptoms of liver damage that you should watch out. Your ankles and legs begin to swell.. Your urine becomes dark yellow in color. There can be many reasons for dark yellow urine, but it can also be a sign of liver damage. Excessively itchy skin is also a symptom of liver damage. Loss of appetite. Getting bruises easily as your liver fails to create proteins needed for blood clotting. Vomiting and nausea for no reason. Blood in the stool or pale stool. Chronic fatigue. How is liver damage diagnosed? In order to get started with the liver damage treatment, it is very important to diagnose the symptoms of liver damage correctly. In order to start the diagnoses, your doctor will start with a physical examination, followed by requesting details of your health history. Liver function tests, which are blood tests will be done at the initial stage. MRI Scan and CT scan kind of image tests are done. Tissue analysis is also done to get an accurate idea of the problem . How is liver damage treated? The treatment for the liver damage depends on the type and severity of damage. Some stages can be treated with just slight modifications to the diet and lifestyle like weight reduction, no smoking or alcohol. Further stages will require medication and severe condition will need a surgery. If your liver has failed completely, then you will have to go for a liver transplant, which is an expensive and time consuming process. How can liver damage be prevented? Certain changes in your lifestyle can prevent liver damage. You need to stop drinking alcohol or only drink a moderate amount to decrease pressure on your liver. Get vaccinated to prevent getting hepatitis infections. When you are spraying insecticides or other aerosol sprays, make sure that you cover your nose and also make sure to protect your skin. You need to maintain a healthy weight as there are chances of fatty liver damage as well. You should take only medicine that is prescribed to you and make sure that you do not take any medicine in excess or without talking to your doctor.
Read More